||The low-cycle fatigue behavior of a duplex stainless steel, 60 % ferrite - 40 % austenite, is studied under tension-compression/torsion loading at room temperature. The influences of loading direction and loading path are analyzed. It is shown that the duplex stainless steel has an isotropic behavior under tension-torsion loading in monotonic as well as in cyclic conditions. The loading path induces an over-hardening on cyclic hardening of duplex stainless steel, but lower than the one on austenitic stainless steels. The effect of loading history is studied in terms of strain amplitude, mean strain and loading path. It is shown that only histories in strain amplitude and loading path have a small effect on the stabilized stress.