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Full-field measurements and identification for biological soft tissues – applications in cardiovascular biomechanics

[ mardi 22-11-2011 17:00 | français ]Full-field measurements and identification for biological soft tissues – applications in cardiovascular biomechanics Stéphane Avril Centre Ingénierie et Santé
Laboratoire Claude Goux
École Nationale Supérieure des Mines de Saint-Etienne

Résumé :
Biological soft tissues appear to develop, grow, remodel, and adapt so as to maintain particular mechanical metrics (e.g., stress) near target values. To accomplish this, tissues often develop regionally varying stiffness and anisotropy. The goal of this work is to develop and implement hybrid experimental - computational method to quantify the local constitutive and fracture properties in situ. To this end, we combine stereo digital image correlation with a custom inverse method to infer, using nonlinear regression, the best-fit material parameters within a postulated form of the stored energy function. Diverse applications will be noted, but the method will be illustrated primarily for results from arteries. Extension of the approach to medical-imaging based data will also be discussed.